Gametogenic genes in cancer
Tumors frequently reactivate genes that are otherwise only expressed in testis, ovary and placenta
RNAi-based functional genomics
We identify gene products that support viability and/or modulate chemotherapeutic sensitivity in tumor cells. Using this strategy, we discovered that tumor cells can depend on aberrantly activated gametogenic genes for survival.
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Angelique Whitehurst, Ph.D.
Associate Professor
Pharmacology | Harold C. Simmons Comprehensive Cancer Center
Cancer Biology, Cell and Molecular Biology
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